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Now Foods, SAM-e (S-Adenosyl-L-Methionine), 400 mg, 60 Tablets

Now Foods, SAM-e (S-Adenosyl-L-Methionine), 400 mg, 60 Tablets

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In Stock
  • Expiration Date: Dec 2018
  • Shipping Weight:
    0.84 lbs
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  • Product Code: NOW-00141
  • UPC Code: 733739001412
  • Package Quantity: 60 Tablets
  • Dimensions:
    2.4 x 2.4 x 4.1 in, 0.5 lbs
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Product Overview


  • Nervous System Support
  • Supports Emotional Well-Being
  • Supports Joint Health
  • Enteric Coated
  • A Dietary Supplement
  • Vegetarian/Vegan
  • GMP Quality Assured

SAMe (S-adenosylmethionine), a compound native to the body, is a critical component of many biochemical reactions, including those that affect brain biochemistry and joint health. Numerous studies have indicated that SAMe can help to temporarily alleviate minor joint discomfort resulting from overexertion or stress. In addition, because SAMe is also necessary for the synthesis of neurotransmitters, it plays an important role in mood support. NOW SAMe is enteric-coated, which makes it very well tolerated and protects it from degradation.

Suggested Use

As a dietary supplement, take 1 tablet 2 to 4 times daily, preferably on an empty stomach.

Refrigeration recommended after opening.

Other Ingredients

Cellulose, croscarmellose sodium, magnesium stearate (vegetable source), silica, stearic acid (vegetable source), ascorbic acid, citric acid and enteric coating (cellulose, triethyl citrate, methacrylic acid.)

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.


Do not eat freshness packet. Keep in bottle.

Caution: For adults only. Individuals with bipolar (manic) depression and those with anxiety disorders should not take SAMe unless under professional medical supervision. Consult physician if pregnant/nursing, taking medication, or have a medical condition. Keep out of reach of children.

Supplement Facts
Serving Size: 1 Tablet
  Amount Per Serving % Daily Value
SAMe (S-Adenosyl-L-Methionine) (from 800 mg of S-Adenosyl-L-Methionine Disulfate Tosylate) 400 mg *
* Daily Value not established.
iHerb Customer Reviews


Posted by 4996436845873956631 on Apr 29, 2017 | Verified Purchase

works as well as any SAMe

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A real life saver

Posted by 5038070293830895939 on Mar 26, 2017 | Verified Purchase

I had been ill for some years and although already on supplements, not making much progress toward getting better. I implored my doctor to find something else and he prescribed Sam-e. It turned my life around and I started getting noticeably better from that day.

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Good ingredients for SAM E

Posted by 5050700604295824697 on Mar 15, 2017 | Verified Purchase

This product has good medicinal and fairly good non medicinal ingredients. A lot of SAM E's are yellow which is dye or has titanium dioxide etc in them which is not good. It does have magnesium stearate which they say isn't great either. So hard to find a perfect product of any kind!

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Posted by 5295707049860405303 on Dec 19, 2016 | Verified Purchase

Good product great service

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Excellent Product

Posted by 4807734581378084172 on Nov 30, 2016 | Verified Purchase

I won't live without this brand of SAM-e. Great for mood enhancement and reduction of joint pain.

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